IRD, Jaipur

 

Research & Publication for Jan-Dec 2018

 

1. Rajawat GS, Singh AK, Kurian T, Koolwal S. A Rare Differential Diagnosis of Crazy Paving Pattern. Indian J Med PaediatrOncol 2018; 39:415-6.

2. Sharma VK, Jain S, Joshi V, Khippal N. Osteoporosis and correlates in chronic obstructive pulmonary disease. RUHS Journal of health sciences 2018; 3:73-77.

3. Jain S, Rathore YS, Joshi V, Khippal N. Clinical, radiological, microbiological profile of pulmonary aspergillosis in treated case of pulmonary tuberculosis. Indian journal of allergy, asthma and immunology 2018 32:74-77.

4. Singh S, Jindal A. A 45-year-old man presenting with chest pain. Lung India 2018; 35:171-2.

5. Singh S, Collins BF, Bairwa M, Joshi JM, Talwar D, Singh N, Samaria JK, Mangal DK, Singh V, Raghu G. Hypersensitivity pneumonitis and its correlation with ambient air pollution in urban India. ERJ 2018. DOI: 10.1183/13993003.01563-2018.

6. Mishra MK, Jain S, Sharma A, Jain VK. Pattern of drug resistance in previously treated pulmonary tuberculosis with line probe assay. Annals of international medical and dental research July-August 2018.

7. Rajawat GS, Meena M, Gupta ML, Arora P. Absent unilateral pulmonary artery: a report of two cases. The journal of association of chest physicians 2018;6:72-5.

8. Rajawat GS, Khippal N, Takhar RP. Poland syndrome with associated symbrachydactyly and dextrocardia: a rare case. International journal of research in medical sciences 2018;6:2860-62.

9. Study of copper, zinc and ceruloplasmin albumin ratio in pulmonary tuberculosis. International Journal of Current Research 2017; 9:49085-49089.

10. Vitamin D in pulmonary tuberculosis patients in relation to disease severity. International Journal of Current Research 2018; 10:71347-71352.

11. Ionic Calcium verses Total Calcium in Relation to Disease Severity and Inflammation in Pulmonary Tuberculosis. International Journal of Medical Science and Current Research 2018; 1:23-32.

12. Joshi V, Jain S, Sharma V, Khippal N, Chaturvedi A. Granulomatous hepatitis with military mottling: a rare cause. Journal of the association of physicians of India 2018;66:79-81.

13. Meena LN, Khippal N, Bhandari C, Jenaw RK, Joshi V, Meena S. Anxiety and depression in chronic obstructive pulmonary diseases. International journal of medical science and innovative research 2018;3:13-15.

14. Jain S, Singh AS, Rathore Y. Clinical Puzzle. RMJ Jan 2018.

 

Awards

Dr Suresh Koolwal

1. Presidential oration award, Indian association of bronchology, Coimbatore, Feb 2018

2. Fellowship of Royal college of physicians, Edinburgh (FRCP)

3. Nominated as National President of Indian Association for Bronchology

 

Dr Sheetu Singh

1. Member of national academy of medical sciences

2. Assistant editor, Lung India

3. Editor, Lung Rajasthan

 

Research Work (Clinical trials - Principal Investigator – Dr. Narendra Khippal)

 

A) COPD - Principal investigator – Dr. Narendra Khippal

1. A Randomized, 26-Week, Placebo-Controlled Efficacy and Safety Study with a 2week Long-term Safety Extension of High and Medium-Dose Inhaled Mometasone Furoate/Formoterol Fixed-Dose Combination Formulation Compared with Formoterol and High-Dose Inhaled Mometasone Furoate Monotherapy in Subjects with Moderate to Severe COPD.

2. A randomized, double-blind, double dummy, multicentre, Parallel- group study comparing the efficacy and safety of the test HFA formulation of lpratropium bromide with the reference HFA formulation of lpratropium bromide in patients with mild or moderate chronic obstructive pulmonary disease (C0PD).

3. An open label comparative multicentric study to assess the efficacy and safety of fixed-dose combination of Formoterol fumarate & Mometasone furoate Dry Powder Inhaler (DPI) and fixed dose combination formoterol fumarate & Budesonide Dry Powder Inhaler {DPI) for the treatment of bronchial asthma and/or chronic obstructive pulmonary disease (COPD).

4. A randomised, double-blind, active-controlled parallel group study to evaluate the effect of 52 weeks of once daily treatment of orally inhaled tiotropium + olodaterol fixed dose combination compared with tiotropium on Chronic Obstructive Pulmonary Disease (COPD) exacerbation in patients with severe to very severe COPD.[DYNAGITO]

  

B) BRONCHIAL ASTHMA- Principal investigator –Dr. Narendra Khippal

5. An open label, comparative, multicentric study to assess the efficacy and safety of Zileuton extended-release tablets in comparison with Montelukast sodium tablets in patients suffering from bronchial asthma.

6. A phase II, 12 week randomized, double-blind, triple dummy, parallel group, placebo-controlled, dose range finding study to evaluate the safety, tolerability and efficacy of revamilast in subjects with chronic persistent Asthma.

7. A prospective, open label, non-comparative, observational, 24 weeks multicenter study of Fluticasone/Formoterol (Maxiflo®) FDC rotacaps (100/6 mcg and 250/6 mcg) when taken through Revolizer® in patients with persistent asthma.

 

C) ALLERGIC RHINITIS - Principal investigator – Dr. Narendra Khippal

8. A randomized, open label, comparative, multicentric study to assess the efficacy and safety of Acrivastine capsules in comparison with Chlorpheniramine maleate tablets in patients suffering from allergic rhinitis.

 

D) DEEP VEIN THROMBOSIS - Principal investigator – Dr. Narendra Khippal

9. International, multi-centre, randomized, double blind study to compare the overall mortality in acutely ill medical patients treated with enoxaparin versus placebo in addition to Graduated Elastic Stockings.

 

E) LUNG CANCER - Principal investigator – Dr. Narendra Khippal

10. A Randomized, double-blind, placebo controlled Phase 2 trial of Bavituximab plus Docetaxel in patients with previously treated locally Advanced or Metastatic Non­ Squamous Non-Small-Cell Lung Cancer.

11. A Randomized, open label, phase 2 trial of Paclitaxel/Carboplatin with or without Bavituzimab in patients with previously untreated locally Advanced or Metastatic Non-Squamous Non-Small-Cell Lung Cancer.

12. Phase 3 Study of Pemetrexed, Cisplatin, and Radiotherapy Followed by Consolidation Pemetrexed versus Etoposide, Cisplatin, and Radiotherapy Followed by Consolidation Cytotoxic Chemotherapy of Choice in Patients with Unresectable, Locally Advanced, Stage III Non-Small Cell Lung Cancer Other than Predominantly Squamous Cell Histology.

13. A phase III, multicenter, randomized, double-blind, unbalanced (3:1) active control study to assess the safety and describe the efficacy of netupitant and palonosetron for the prevention of chemotherapy-induced nausea and vomiting in repeated chemotherapy cycles.

 

F) Community acquired pneumonia -Principal investigator – Dr. Narendra Khippal

14. A Phase III, Multicentre, Randomized, Double-Blind, Comparative Study to Evaluate the Efficacy and Safety of Intravenous CeftarolineFosamil Versus Intravenous Ceftriaxone in the Treatment of Adult Hospitalised Patients With Community­Acquired Bacterial Pneumonia in Asia.

15. A Randomized, Double-blind, Double-dummy, Active-controlled, Multi-centre Trial to Compare the Efficacy and Safety of CSE-1034 (Ceftriaxone+ Sulbactam+ EOTA) with Meropenem in Infections Caused by -Lactamase (ESBL and MBL) producing Gram Negative Bacteria.

16. A Randomized, Multicentre, Double-blind, Double-dummy, Parallel-group Comparative Study to Determine the Efficacy, Safety And Tolerability of Ceftazidime-Avibactam (CAZ-AVI) Versus Meropenem in the Treatment of Nosocomial Pneumonia (NP) Including Ventilator-Associated Pneumonia (VAP) in Hospitalised Adults.

 

G) HIV - Principal investigator – Dr. Narendra Khippal

17. A prospective, multi-centre, double-blind, randomized, study to evaluate the safety and efficacy of Saroglitazar 4mg versus Placebo in the treatment of HIV associated lipodystrophy.

 

List of Publications 2017 to present

 

Dr Shashi Agnihotri

1. A.K Mehrotra, S.P. Agnihotri : Study of recurrence in DOTs cured and completed treatment patients international Journal of medical science and education, Vol.4 issue.4, 2017

2. Bairwa Manish Kumar, Agnihotri S.P., Qureshi Mohammad J. charcterzation of microbiologial pattern in Brochiectasis patients Global Journal of Research analysis Vol.8 issue 2 Feb-2019

3. Gupta Rahul, Agnihotri S.P., Qureshi Mohammad J.  Correlation of Chest Computed tomography findings with six minute walk distance in people with post tubercular sequelae. Vol.8 issue 5, May, 2019

4. Ajith K., Singh A.K., Agnihotri S.P. “A study on Serum CRP and its Correlation with disease severity in stable COPD.” International Journal of Scientific research [IJSR 2020;9(2),56-58]

5. Gaur J.K., Singh A.K., Agnihotri S.P. “The changing Microbiological patterns of community acquired pneumonia.” Indian Journal of applied research Vol.10 issue 2, 51-52, Feb-2020.

6. Manish Kumar Meena, Aashish K. Singh, Shashi Prakash Agnihotri Corelation of 6 minute walk test with Clinico radiological parameters in stable COPD patients International Journal of Scientific research Vol.9 issue to February, 2020

 

Dr. Vinod Joshi

1.  Clinical, Radiological and Microbiological Profile of Pulmonary Aspergillosis in treated case of Pulmonary T.B. Shubhra Jain, Yogendra Rathore, Vinod Joshi, Narendra Khippal Indian Journal of Allergy, Asthma & immunology..  Vol. 32/issue 2/july- december 2018

2.  Osteoporosis and its correlation in COPD. Vinod Joshi, Shubhra Jain, Vinod Sharma. RUHS Journal of Health Science. Vol.3/Number.2/ April –June 2018.

3.  Clinical Radiological & etiological profile of patient with SVC Syndrom in indian scenario. Shubhra Jain, Mahesh Mishra, Vinod Joshi, PJCM 2018; 24(4)

4.  Case report – Cryptogenic organizing pneumonia mimicking a mass lesion; An unusual case. Shubhra Jain, Yogendra Rathore, Anshika Jindal, Vinod Joshi Indian Journal Respiratory Care 2019,8,124-6

5. Erasmus syndrome: Silicosis & systemic sclerosis, Jain S, Joshi V, Rathore YS, Indian Journal of occupational Environment Medicine 2017; 21:94-96.

6. Mediastinal Aspergilloma: An unusual presentation as SVC obstruction. N Khippal, Anshika Jindal, Yogendra Rathore, Vinod Joshi, Shubhra Jain.The Egyption Journal of Chest Diseases and Tuberculosis. 2020, 69, 272-275  

 

Dr. Suresh Koolwal

1. Study of iron metabolism in pulmonary tuberculosis patients. Int J Health Sci Res. 2018; 8(3):70-77.

2. ASSESSMENT OF INDICATORS OF MALNUTRITION IN COPD PATIENTS GLOBAL JOURNAL FOR RESEARCH ANALYSIS VOLUME-8, ISSUE-6, JUNE-2019 • PRINT ISSN No. 2277 – 8160

3.      A rare differential diagnosis of crazy paving pattern.Indian J Med Paediatr Oncol 2018; 39:415-416

 

Dr Nalin Joshi

1. Joshi N. Systemic Scelrosis, Sine Scleroderma: An rare EMTY, Indian Journal of Chest Diseases & Allied sci.

 

Dr Chand Bhandari

1. Sirowa M, Meena RC, Soothwal P, Bhandari C, Gupta PR, Bhangoo HS. Role of medical thoracoscopy in undiagnosed exudative pleural effusion. Ind J Basic Applied Medical Research 2017;7:282-87.

2. Khatri R, Meena RC, Gupta PR, Meena S, Bhandari C, Bhangoo HS. Place of active case findingacctivity in detection of relapses in treated patients of DOTS Cat 1 patients. Ind J Basic Applied Medical Research 2017;7:149-55.

 

Dr Shubhra Jain

7.  “Pattern of Drug resistance in previously treated pulmonary T.B with line probe assay”. Mahesh Mishra, Shubhra Jain, Akansha, V.K. Jain Annuals of international medical & Dental Research July  - Aug 2018

8.      Clinical, Radiological and Microbiological Profile of Pulmonary Aspergillosis in treated case of Pulmonary T.B. Shubhra Jain, YogendraRathore, Vinod Joshi, NarendraKhippal Indian Journal of Allergy, Asthma & immunology..  Vol. 32/issue 2/july- december 2018

9.      Osteoporosis and its correlation in COPD. Vinod Joshi, Shubhra Jain, Vinod Sharma. RUSH Journal of Health Science. Vol.3/Number.2/ April –June 2018.

10.  Clinical Radiological & etiological profile of patient with SVC Syndrom in indian scenario. Shubhra Jain, Mahesh Mishra, Vinod Joshi, PJCM 2018; 24(4)

11.  Case report – Cryptogenic organizing pneumonia mimicking a mass lesion; An unusual case. Shubhra Jain, YogendraRathore, Anshika Jindal, Vinod Joshi Indian Journal Respiratory Care 2019,8,124-6

12.  Erasmus syndrome: Silicosis & systemic sclerosis, Jain S, Joshi V, Rathore YS, Indian Journal of occupational Environment Medicine 2017; 21:94-96.

13.  Mediastinal Aspergilloma: An unusual presentation as SVC obstruction. N Khippal, Anshika Jindal, Yogendra Rathore, Vinod Joshi, Shubhra Jain. The Egyption Journal of Chest Diseases and Tuberculosis. 2020, 69,272-275

 

Dr. Sheetu Singh

1. Singh S, Collins BF, Sharma BB et al. Interstitial Lung Disease (ILD) in India: Results of a Prospective Registry. Am J RespCrit Care Med 2017;195:801-13.

2. Singh S, Collins BF, Singh V, Raghu G. "Reply: "The ILD-India Registry: Ignoratio Elenchi" and "The ILD-India Registry: Look Before You Leap". Am J RespCrit Care Med 2017; 195:837-39.

3. Singh S, Jindal A. A 45-year-old man presenting with chest pain. Lung India 2018;35:171-2.

4. Singh S, Collins BF, Bairwa M, Joshi JM, Talwar D, Singh N, Samaria JK, Mangal DK, Singh V, Raghu G. Hypersensitivity pneumonitis and its correlation with ambient air pollution in urban India. EurRespir J. 2019 Jan 31; 53(2). pii: 1801563.

5. Singh N, Singh S, Singh V. Learning curve: Endobronchial ultrasound-guided needle aspiration. Lung India 2019; 36:178-79.

6. Singh N, Singh S, Singh V. Six month follow up outcome data of endobronchial ultrasound guided transbronchial aspiration in patients with undiagnosed mediastinal lymphadenopathy. Thoracic endoscopy 2018; 3:47-51.

7. Shekhar K, Bagarhatta R, Singh S, Sharma SK. Warfarin-induced diffuse alveolar hemorrhage: Case report and review of literature. Lung India 2019; 36:534-9.

8. Dhar R, Singh S, Talwar D, Mohan M, Tripathi SK, Swarnakar R, et al. Bronchiectasis in India: results from the European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC) and Respiratory Research Network of India Registry. The Lancet Global Health. 2019;7(9):e1269-e79.

9. Mohan A, Madan K, Hadda V, Tiwari P, Mittal S, GuleriaR, Singh S, et al. Guidelines for diagnostic flexible bronchoscopy in adults: Joint Indian Chest Society/National College of chest physicians (I)/Indian association for bronchology recommendations. Lung India 2019;36(8):37-89.

10. Singh S, Collins BF, Sharma BB, Joshi JM, Talwar D, Katiyar S, et al. Hypersensitivity pneumonitis: Clinical manifestations – Prospective data from the interstitial lung disease‑India registry. Lung India 2019;36:476-82.

11. Sharma B, Singh S, Sharma K, Suraj K, Mahmood T, Samaria K, et al. Methodology of Seasonal Waves of Respiratory Disorders survey conducted at respiratory outpatient clinics across India. Lung India 2020;37(2):100-6.

12. Singh S, Sharma BB. Severe acute respiratory syndrome-coronavirus 2 and novel coronavirus disease 2019: An extraordinary pandemic. Lung India 2020;37(3):268-271.

13. Singh S, Sharma N, Singh U, Singh T, Mangal DK, Singh V. Rapid Systematic Review: Nasopharyngeal wash in preventing and treating upper respiratory tract infections: Could it prevent COVID-19? Lung India 2020;37(3):246-251.

14. Singh S, Sharma BB, Bairwa M, et al. Management of interstitial lung diseases: A consensus statement of the Indian Chest Society (ICS) and National College of Chest Physicians (NCCP). Lung India. 2020;37(4):359-378. 

 

 Dr. Aashish Singh

1. G.S. Rajawat, A.K.Singh, S. Koolwal “A Rare Differential Diagnosis of Crazy Paving Pattern.” [Ind J Med & Ped Oncology 2018;39:415-6]

2. Samaria M, Singh A.K., Joshi N. “Depression associated with multi drug resistant tuberculosis.”[GJRA 2019; 8(2),1-3].

3. Unchwal M, Singh A.K., Joshi N. “A Study on Neutrophil Lymphocyte Ratio and Platelet Lymphocyte Ratio with disease severity in stable and exacerbation of COPD.” [Paripex 2020;9(1),16-17]

4. Meena M, Singh A.K., Agnihotri S.P. “Correlation of 6 minute walk test with clinic-radiological parameters in stable COPD patients.” [IJSR 2020;9(2),48-49]

5. Ajith K., Singh A.K., Agnihotri S.P. “A study on Serum CRP and its Correlation with disease severity in stable COPD.” [IJSR 2020;9(2),56-58]

6. Gaur J.K., Singh A.K., Agnihotri S.P. “The changing Microbiological patterns of community acquired pneumonia.” [IJAR 2020;9(2),51-52]

7. Meena R.L., Singh A.K., Joshi N. “The Lactate-Albumin Ratio: a valuable tool for predicting outcome in Respiratory ICU patients.” [Paripex 2020;9(2),12-13]

8. Gupta S.K., Singh A.K., Meena A.S., Bajpai A. “A study to investigate the prevalence of metabolic and metabolic like syndrome in stable COPD patients.” [GJRA 2020;9(2),3-5]

9. Gupta S.K., Singh A.K..“A study to investigate the prevalence of metabolic syndrome in stable COPD patients.” [GJRA 2020;9(2),3-4]

 

Dr. Govind Singh Rajawat

1. Rajawat GS, Batra S, Takhar RP, Rathi L, Bhandari C, Gupta ML. Diagnostic yield and safety of closed needle pleural biopsy in exudative pleural effusion. Avicenna J Med 2017; 7:121-4.

2. Batra S, Rajawat GS, Takhar RP, Gupta ML. Pattern and predictors of paradoxical response in patients with peripheral lymph node tuberculosis TuberkToraks2017;65(3):180-185.

3. Rajawat GS, Meena M, Gupta ML, Arora P. Absent Unilateral Pulmonary Artery: A Report of Two Cases. J Assoc Chest Physicians 2018;6:72-5.

4. Rajawat GS, Singh AK, Kurian T, Koolwal S. A rare differential diagnosis of crazy paving pattern. Indian J Med PaediatrOncol2018;39:415-6.

5. Rajawat GS, Khippal N, Takhar RP. Poland syndrome with associated synbrachydactyly and dextrocardia: a rare case. Int J Res Med Sci 2018;6:2860-2.

6. Amardeepak Toppo, Gulabsingh Yadav, Govindsingh Rajawat, Thomas Kuriyan, Suresh koolwal Assessment Of Indicators Of Malnutrition In COPD Patients GJRA 2019 volume-8, issue-6, PRINT ISSN No. 2277 – 8160.

7. Bidyalakshmee Yumnam, Govind Singh Rajawat, Suresh Koolwal Assessment Of Inhalational Techniques And Changes Occurs After Imparting Education In Patients Of Obstructive Airway Diseases. VGjra 2019 Volume-8, Issue-4, Print Issn No. 2277 – 8160.

8. Govind Singh Rajawat, Mohammed JavedQureshi, Gulab Singh Yadav, Yumnam Bidyalakshmee, Suresh Koolwal, ManoharLal Gupta. Identifying the Factors Increasing the Yield of Closed Pleural Biopsy in Undiagnosed Exudative Pleural Effusion, The RMJ Issue Jan 2019 ISSN: 0485-9561Issue : Jan 2019; 19-22.

 

Dr Gulab Singh Yadav

9. Study of various reason for Interruption of Antitubercular treatment in patients of tuberculosis reporting to tertiary care center of West Rajasthan. International Journal of Research in Medical Science /June 2019/Vol. 7/Issue 6/ Page 2220

10.  Assessments of Indicators of Malnutrition in COPD patients. Global Journal for Research Analysis. Vol.8/ Issue 6/ June 2019/ Print ISSN No. 2277-8160

 

Dr Mohammad Javed Qureshi

1. Bairwa Manish Kumar, Agnihotri S.P., Qureshi Mohammed J. charcterzation of microbiologial pattern in Brochiectasis patients Global Journal of Research analysis Vol.8 issue 2 Feb-2019

2.  Gupta Rahul, Agnihotri S.P., Qureshi Mohammed J. Correlation of Chest Computed tomography findings with six minute walk distance in people with post tubercular sequelae. Vol.8 issue 5, May, 2019

3. Identifying the Factors Increasing the Yield of Closed Pleural Biopsy in Undiagnosed Exudative Pleural Effusion Govind Singh Rajawat, Mohammed Javed Qureshi, Gulab Singh Yadav, Yumnam Bidyalakshmee, Suresh Koolwal, ManoharLal Gupta, (page.19) ISSN : 0485-9561 [Rajasthan medical journal]  Issue : Jan 2019

 

Dr. Manoj Meena

1.  1. G.N Srivastava,ManojMeena, Clinical tools and biochemical markers to assess short term mortality in Acute exacerbation of COPD. Journal Of Clinical Diagnosis &Research,JCDR/2018/JULY vol 12(7)OC16:OC 19